Screen Shot 2018-04-16 at 20.05.28 Published 16. April 2018 at 1028 × 434 in Low complexity pooling does not prevent siRNA off-targets ← Previous / Next → Related Posts:ON-TARGETplus siRNAs have strong off-target effects (despite…The Iron Law of RNAi ScreeningsiPOOLs: robust reagents for gene silencingChemical modifications only shift the siRNA seed profile